Course Introduction

Data

Data

binary data
Individual mobile phone plan data remaining.
Cambridge Analytica (2013-2018) corporate logo
Russian group, Midnight Blizzard, accessed by Microsoft corporate as well as customer email in the first half of 2024.
National Public Data, a background check service, reports theft of ~134 million unique records potentially including name, ssn, postal and email addresses.
National Public Data, a background check service, published their own master database passwds.
Krebs on Security
Right to be forgotten form @ google.com, not for US citizens.
National Health Service cookie notice.
www.nhs.uk
Social media icons, more or less.
Sequence Read Archive growth since 2009, NIH.
Sequence Read Archive @ NIH
Protein Data Bank growth since 1976.
PDB Stats @ rcsb.org
European Nucleotide Archive growth since 1982.
ENA Statistics
1000 Cannabis project public data announcement, Medium.com.
DNA Sequencing of 1000 Cannabis Strains publicly available in Google BigQuery

FASTA


>Chain A, CRYSTAL STRUCTURE OF RNASE T1 WITH 3'-GMP AND GUANOSINE: A PRODUCT
COMPLEX
        
ACDYTCGSNCYSSSDVSTAQAAGYKLHEDGETVGSNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFN
ENNQLAGVITHTGASGNNFVECT

Lipman DJ and Pearson WR (1985) Rapid and sensitive protein similarity searches Science 227: 1345-41.

Meme representation of secretory signal sequence from P. falciparum.
Bailey TL, Johnson J, Grant CE and Noble WS (2015) The MEME suiteNucleic Acids Res 43: W39-W49.

FASTQ

@This is a short sequence
		  

		GCATACCGCAGTCGACTCGTA
		  

		+
		  

		  !'))FGVHII[abacdbac(!

Quality scores, low to high

!"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~

Cock PJA, Fields CJ, Goto N, Heuer ML and Rice PM (2010) The Sanger FASTQ file format for sequences with quality scores, and the Solexa/Illumina FASTQ variants Nucleic Acids Res 38: 1767-71.

PDB

 
ATOM     32  N   THR A   5       8.318   1.454   8.777  1.00  9.53           N
  
ATOM     33  CA  THR A   5       9.128   0.477   8.010  1.00  9.06           C
  
ATOM     34  C   THR A   5       9.652   1.192   6.734  1.00  8.76           C
  
ATOM     35  O   THR A   5       8.805   1.679   5.987  1.00 10.45           O
  
ATOM     36  CB ATHR A   5       8.295  -0.786   7.598  0.50 10.51           C
ATOM     37  CB BTHR A   5       8.338  -0.785   7.522  0.50  8.84           C
ATOM     38  OG1ATHR A   5       8.191  -1.556   8.858  0.50 11.07           O
ATOM     39  OG1BTHR A   5       7.390  -1.287   8.528  0.50  8.05           O
ATOM     40  CG2ATHR A   5       8.800  -1.735   6.504  0.50 10.11           C
ATOM     41  CG2BTHR A   5       9.366  -1.870   7.129  0.50 13.39           C

Bernstein, FC, Koetzle, TF, Williams, GJ, Meyer EE, Brice MD, Rodgers JR, Kennard, O, Shimanouchi, T and Tasumi, M (1977) The Protein Data Bank: a computer-based archival file for macromolecular structures J Mol Biol 112 53542.

Biochemical Data Growth